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| 04:00 Austin – Dallas : | 2.90 | 4.00 | 2.29 | X2 | 1-2 | O |
|
| 04:30 Santos Laguna – Guadalajara : | 5.73 | 4.40 | 1.49 | 2 | 1-2 | O |
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| 04:45 Once Caldas – Alianza Valledupar : | 1.57 | 3.64 | 6.16 | 1 | 2-1 | U |
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| 06:00 Seattle Sounders – Vancouver Whitecaps : | 3.61 | 4.27 | 1.92 | 2 | 1-2 | O |
|
| 06:30 Tijuana – Cruz Azul : | 3.08 | 3.20 | 2.29 | 1X | 2-1 | U |
|
| 18:30 Gnistan – Ilves : | 2.38 | 3.54 | 2.71 | 1X | 2-1 | O |
|
| 18:30 Polissya Zhytomyr – Zorya Luhansk : | 1.54 | 4.16 | 6.30 | 1 | 2-1 | U |
|
| 19:00 Qarabag – Shamakhi : | 1.46 | 4.05 | 5.87 | 1 | 2-1 | O |
|
| 19:00 Zalaegerszegi – Ferencvarosi : | 6.12 | 3.78 | 1.49 | 2 | 1-2 | O |
|
| 19:00 Universitatea Cluj – UTA Arad : | 1.97 | 3.34 | 3.74 | 1 | 2-1 | O |
|
| 19:30 Spartak Varna – Septemvri Sofia : | 1.90 | 3.30 | 4.10 | 1 | 2-1 | U |
|
| 19:30 Birkirkara – Gzira United : | 2.19 | 3.02 | 3.20 | 1X | 1-0 | U |
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| 20:30 Spartak Varna – Septemvri Sofia : | 1.89 | 3.32 | 4.10 | 1 | 2-1 | U |
|
| 20:30 Brondby – SonderjyskE : | 1.39 | 4.80 | 7.18 | 1 | 2-1 | O |
|
| 20:30 Felgueiras 1932 – Aves : | 2.32 | 3.12 | 3.14 | 1X | 2-1 | O |
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| 20:30 Sporting de Gijon – Sabadell : | 1.83 | 3.54 | 4.68 | 1 | 2-1 | U |
|
| 20:30 Hacken – Halmstads : | 1.31 | 5.55 | 8.00 | X2 | 2-2 | O |
|
| 21:15 Estudiantes de Rio Cuarto – Atletico Tucuman : | 3.08 | 2.79 | 2.71 | 1X | 2-1 | U |
|
| 21:30 Liege – Francs Borains : | 1.96 | 3.40 | 3.38 | 1 | 2-1 | U |
|
| 21:30 Valur – Knattspyrnufelag Akureyrar : | 2.04 | 3.92 | 3.04 | 1X | 2-1 | O |
|
| 21:30 De Graafschap – AZ Alkmaar II : | 1.73 | 4.45 | 3.68 | X2 | 1-2 | O |
| 21:30 AFC Ajax II – Emmen : | 2.89 | 3.74 | 2.17 | X2 | 1-2 | O |
| 21:30 Utrecht II – Vitesse : | 3.36 | 3.74 | 1.97 | 1X | 2-1 | O |
|
| 21:30 Novi Pazar – Vojvodina Novi Sad : | 3.44 | 3.54 | 1.90 | 2 | 1-2 | U |
|
| 21:45 Arda Kardzhali – Lokomotiv Sofia : | 1.83 | 3.46 | 4.20 | 1 | 2-1 | U |
|
| 22:00 Hamrun Spartans – Mosta : | 1.14 | 5.90 | 14.50 | 1 | 2-1 | O |
|
| 22:00 FCSB – Botosani : | 1.51 | 4.20 | 5.79 | 1 | 2-1 | O |
|
| 22:00 Samsunspor – Goztepe : | 2.27 | 3.39 | 3.39 | 1X | 1-0 | U |
|
| 22:00 Batman Petrolspor – Boluspor : | 1.48 | 4.10 | 5.54 | X2 | 1-2 | O |
|
| 22:30 Cardiff City – Wrexham : | 2.44 | 3.34 | 2.76 | 1X | 2-1 | U |
|
| 22:30 Deportivo de La Coruna – Elche : | 2.39 | 3.17 | 3.56 | 1X | 2-1 | U |
|
| 22:45 Knattspyrnufelagid Fram – Stjarnan : | 1.90 | 4.25 | 3.22 | 1 | 2-1 | O |
|
| 23:00 UD Almeria – Eldense : | 1.34 | 5.53 | 8.65 | 1 | 2-1 | O |
|
| 23:30 Club Atletico Lanus – CA Independiente Avellaneda : | 2.33 | 2.91 | 3.56 | 1X | 2-1 | U |
|
| 00:35 Atletico Bucaramanga – Deportivo Pasto : | 1.57 | 3.62 | 6.25 | 1X | 2-1 | U |
|
| 01:30 Montevideo Wanderers – Cerro Largo : | 2.16 | 3.02 | 3.27 | 1X | 2-1 | U |
|
| 01:45 Velez Sarsfield – Defensa y Justicia : | 1.79 | 3.52 | 4.74 | 1X | 2-1 | U |
|
| 02:30 Sport Club Internacional – Clube do Remo : | 1.60 | 4.10 | 5.86 | X2 | 1-2 | U |
|
| 02:40 Millonarios – Deportivo Cali : | 1.71 | 3.42 | 5.11 | 1X | 2-1 | U |
